PCBD1 Polyclonal Antibody
Catalog Number
RD219099A
Western blot analysis of Mouse kidney tissue lysate using PCBD1 Polyclonal Antibody at dilution of 1:800
Immunohistochemistry of paraffin-embedded Human breast cancer tissue using PCBD1 Polyclonal Antibody at dilution of 1:60(×200)
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PCBD1 Polyclonal Antibody at dilution of 1:60(×200)
Variation
Quantity
For more information on our kits, please contact us at info@reddotbiotech.com
Overview
Product Name
PCBD1 Polyclonal Antibody
Catalog Number
RD219099A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a member of the pterin-4-alpha-carbinolamine dehydratase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The encoded protein functions as both a dehydratase involved in tetrahydrobiopterin biosynthesis, and as a cofactor for HNF1A-dependent transcription. A deficiency of this enzyme leads to hyperphenylalaninemia. Alternative splicing results in multiple transcript variants.
Immunogen Information
Immunogen
Fusion protein of human PCBD1
Swissprot
P61457
Synonyms
4 alpha hydroxy tetrahydropterin dehydratase4-alpha-hydroxy-tetrahydropterin dehydratase6 pyruvoyl tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1)6 pyruvoyl tetrahydropterin synthase/dimerization cofactor of
Calculated MW
12 kDa
Observed MW
Refer to figures
Gene Accession
BC006324
Applications
Reactivity
Human, Mouse, Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000
Concentration
1.02 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.