PE Anti-Human CD16 Antibody
Catalog Number
RD20203F
Human pheripheral blood cells are stained with Anti-Human CD16 Monoclonal Antibody(PE Conjugated)(filled gray histogram). Unstained pheripheral blood cells (blank black histogram) are used as control.
Variation
Quantity
For more information on our kits, please contact us at info@reddotbiotech.com
Overview
Product Name
PE Anti-Human CD16 Antibody
Catalog Number
RD20203F
Isotype
Mouse IgG1, κ
Host
Mouse
Background
CD16 is known as low affinity IgG receptor III (FcγRIII). It is expressed as two distinct forms (CD16a and CD16b). CD16a (FcγRIIIA) is a 50-65 kD polypeptide-anchored transmembrane protein. It is expressed on the surface of NK cells, activated monocytes, macrophages, and placental trophoblasts in humans. CD16b (FcγRIIIB) is a 48 kD glycosylphosphatidylinositol (GPI)-anchored protein. Its extracellular domain is over 95% homologous to that of CD16a, and it is expressed specifically on neutrophils. CD16 binds aggregated IgG or IgG-antigen complex which functions in NK cell activation, phagocytosis, and antibody-dependent cell-mediated cytotoxicity (ADCC).
Immunogen Information
Gene ID
2214
Swissprot
P08637
Synonyms
Low affinity immunoglobulin gamma Fc region receptor III-AFCGR3ACD16a antigenFc-gamma RIII-alphaFc-gamma RIIIFc-gamma RIIIaFcRIIIFcRIIIaFcR-10IgG Fc receptor III-2CD16a
Applications
Reactivity
Human
Tested Applications
FCM
Conjugation
PE
Storage Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Instructions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.