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Overview
Product Name
PE/Cyanine7 Anti-Mouse CD183/CXCR3 Antibody
Catalog Number
RD21397F
Clonality
Monoclonal
Isotype
Armenian Hamster IgG
Host
Armenian Hamster
Background
CD183/CXCR3, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes.
Immunogen Information
Gene ID
12766
Swissprot
O88410
Synonyms
C-X-C chemokine receptor type 3Cxcr3CXC-R3CXCR-3Interferon-inducible protein 10 receptorIP-10 receptorCD183/CXCR3