PFKM Polyclonal Antibody

Catalog Number
RD218753A
Western blot analysis of Mouse brain tissue lysate  using PFKM Polyclonal Antibody at dilution of 1:350
Western blot analysis of Mouse brain tissue lysate using PFKM Polyclonal Antibody at dilution of 1:350
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue  using PFKM Polyclonal Antibody at dilution of 1:60(×200)
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PFKM Polyclonal Antibody at dilution of 1:60(×200)
Immunohistochemistry of paraffin-embedded Human liver cancer tissue  using PFKM Polyclonal Antibody at dilution of 1:60(×200)
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using PFKM Polyclonal Antibody at dilution of 1:60(×200)
Variation
Quantity
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Overview
Circle
Product Name
PFKM Polyclonal Antibody
Catalog Number
RD218753A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
Circle
Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described.
Immunogen Information
Circle
Immunogen
Fusion protein of human PFKM
Swissprot
P08237
Synonyms
6 Phosphofructokinase Muscle Type6-phosphofructokinase6-phosphofructokinase muscle typeEC 2.7.1.1EC 2.7.1.11GSD7K6PFMGC8699muscle typePFKmuscle typePFK-APFKAPFKLPFKMPFKPPFKXPhosphofructo 1 Kinase Isozyme APhosphofructo-1-kinase isozyme A
Calculated MW
85 kDa
Observed MW
Refer to figures
Gene Accession
BC021203
Applications
Circle
Reactivity
Human, Mouse, Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000
Concentration
1.02 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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