The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Progesterone receptor isoform B (PRB) is involved activation of c-SRC/MAPK signaling on hormone stimulation.Isoform A: inactive in stimulating c-Src/MAPK signaling on hormone stimulation.Isoform 4: Increases mitochondrial membrane potential and cellular respiration upon stimulation by progesterone.
Immunogen Information
Immunogen
Synthetic Peptide
Swissprot
P06401
Synonyms
NR3C3Nuclear receptor subfamily 3 group C member 3PGRPRPRAPRBPRGRProgesterone receptorProgestin receptor form AProgestin receptor form B
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC-p,IF
Conjugation
Unconjugated
Dilution
IHC 1:100-1:300, IF 1:100-200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.