PHLPP1 Polyclonal Antibody
Catalog Number
RD85334A
Immunofluorescence analysis of U-2 OS cells using PHLPP1 Polyclonal Antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Variation
Quantity
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Overview
Product Name
PHLPP1 Polyclonal Antibody
Catalog Number
RD85334A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a member of the serine/threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine/threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling.
Immunogen Information
Immunogen
Recombinant fusion protein of human PHLPP1 (NP_919431.2).
Gene ID
23239
Swissprot
O60346
Synonyms
PHLPP1PHLPPPLEKHE1PPM3ASCOP
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IF
Conjugation
Unconjugated
Dilution
IF 1:50-1:200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas