Phospho-EEF2K (Ser366) Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD85985A
Western Blot analysis of Hela cells with Phospho-eEF2K (Ser366) Polyclonal Antibody at dilution of 1:1000
Variation
Quantity
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Overview
Product Name
Phospho-EEF2K (Ser366) Polyclonal Antibody
Catalog Number
RD85985A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment.
Immunogen Information
Immunogen
Synthesized peptide derived from human eEF2K around the phosphorylation site of Ser366
Swissprot
O00418
Synonyms
C86191Calcium/calmodulin dependent eukaryotic elongation factor 2Calcium/calmodulin dependent eukaryotic elongation factor 2 kinaseCalcium/calmodulin-dependent eukaryotic elongation factor 2 kinaseCalmodulin dependent protein kinase IIIcb365EC 2.7.1
Calculated MW
82 kDa
Observed MW
105 kDa
Applications
Reactivity
Human,Rat
Tested Applications
WB,IHC-p,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas