Phospho-HDAC6 (Ser22) Polyclonal Antibody
Catalog Number
RD86048A
Western Blot analysis of 3T3 cells with Phospho-HDAC6 (Ser22) Polyclonal Antibody at dilution of 1:500
Variation
Quantity
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Overview
Product Name
Phospho-HDAC6 (Ser22) Polyclonal Antibody
Catalog Number
RD86048A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin.
Immunogen Information
Immunogen
Synthesized peptide derived from human HDAC6 around the phosphorylation site of Ser22
Swissprot
Q9UBN7
Synonyms
CPBHMFLJ16239HD 6HD6HDAC 6HDAC6HDAC6Histone deacetylase 6 (HD6)Histone deacetylase 6JM 21JM21KIAA0901OTTHUMP00000032398OTTHUMP00000197663PPP1R90Protein phosphatase 1 regulatory subunit 90
Calculated MW
131 kDa
Observed MW
131 kDa
Applications
Reactivity
Human,Mouse
Tested Applications
WB,IHC-p,IF,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas