Western blot analysis of extracts of HeLa cells using Phospho-HSPB1(S78) Polyclonal Antibody at dilution of 1:1000. HeLa cells were treated by UV for 15-30 minutes or treated by serum-starvation overnight or treated by Anisomycin (25ug/ml) for 30 minutes after serum-starvation overnight.
Immunohistochemistry of paraffin-embedded Human breast carcinoma using Phospho-HSPB1(S78) Polyclonal Antibody
Immunofluorescence analysis of methanol-fixed HeLa cells showing cytoplasmic, nuclear, centrosomal, midbody staining using Phospho-HSPB1(S78) Polyclonal Antibody
The protein encoded by this gene is induced by environmental stress and developmental changes. The encoded protein is involved in stress resistance and actin organization and translocates from the cytoplasm to the nucleus upon stress induction. Defects in this gene are a cause of Charcot-Marie-Tooth disease type 2F (CMT2F) and distal hereditary motor neuropathy (dHMN).
Immunogen Information
Immunogen
A phospho specific peptide corresponding to residues surrounding S78 of human HSPB1