Phospho-IRF3(S396) Polyclonal Antibody

Catalog Number
RD268195A
Western blot analysis of extracts of HCT116 cells using Phospho-IRF3(S396) Polyclonal Antibody at dilution of 1:1000.
Western blot analysis of extracts of HCT116 cells using Phospho-IRF3(S396) Polyclonal Antibody at dilution of 1:1000.
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Overview
Circle
Product Name
Phospho-IRF3(S396) Polyclonal Antibody
Catalog Number
RD268195A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Circle
This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Immunogen Information
Circle
Immunogen
A phospho specific peptide corresponding to residues surrounding S396 of human IRF3
Gene ID
3661
Swissprot
Q14653
Synonyms
IIAE7IRF3
Calculated MW
12 kDa/16 kDa/33 kDa/47 kDa/49 kDa
Observed MW
55 kDa
Applications
Circle
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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