Phospho-JAK3 (Tyr785) Polyclonal Antibody
Catalog Number
RD86146A
Western Blot analysis of 453 cells with Phospho-JAK3 (Tyr785) Polyclonal Antibody at dilution of 1:1000
Variation
Quantity
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Overview
Product Name
Phospho-JAK3 (Tyr785) Polyclonal Antibody
Catalog Number
RD86146A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).
Immunogen Information
Immunogen
Synthesized peptide derived from human JAK3 around the phosphorylation site of Tyr785
Swissprot
P52333
Synonyms
EC 2.7.10.2JAK 3JAK LJAK-3Jak3JAK3 HUMANJAK3JAKLJanus kinase 3 (a protein tyrosine kinaseleukocyte)Janus kinase 3Janus Kinase3L JAKL-JAKLeukocyte janus kinaseLJAKProtein tyrosine kinase leukocyteTyrosine protein kinase JAK3Tyrosine-prote
Calculated MW
125 kDa
Observed MW
125 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC-p,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:5000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas