PI 3 kinase p85 alpha Polyclonal Antibody
Catalog Number
RD70570A
Western Blot analysis of various samples using PI 3 kinase p85 alpha Polyclonal Antibody at dilution of 1:1000.
Variation
Quantity
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Overview
Product Name
PI 3 kinase p85 alpha Polyclonal Antibody
Catalog Number
RD70570A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Phosphatidylinositol 3-kinase (PI3K) plays an important role in the metabolic actions of insulin and is required for adipogenesis. The PI3K pathway has also been identified as an important player in cancer development and progression. The Class IA PI3K heterodimer,which is composed of a P110 catalytic subunit and a P85 regulatory subunit,is activated upon association of the P85 subunit with upstream adaptor proteins or receptor tyrosine kinases. Mutations in PIK3R1 are implicated in cases of breast cancer and associated to SHORT syndrome.
Immunogen Information
Immunogen
Recombinant protein corresponding to Human PI 3 Kinase p85 alpha.
Swissprot
P27986,P26450,Q63787
Synonyms
GRB1p85 alphap85P85APhosphatidylinositol 3 kinase associated p 85 alphaPhosphatidylinositol 3 kinase regulatory 1Phosphatidylinositol 3 kinaseregulatory subunitpolypeptide 1 (p85 alpha)Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha
Calculated MW
85 kDa
Observed MW
95 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1.6 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas