PRPF8 Polyclonal Antibody
Catalog Number
RD217841A
Western blot analysis of 293T cell lysates using PRPF8 Polyclonal Antibody at dilution of 1:450
Variation
Quantity
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Overview
Product Name
PRPF8 Polyclonal Antibody
Catalog Number
RD217841A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa.
Immunogen Information
Immunogen
Synthetic peptide of human PRPF8
Swissprot
Q6P2Q9
Synonyms
220 kDa U5 snRNP specific protein220 kDa U5 snRNP-specific proteinApoptosis regulated protein 1Apoptosis regulated protein 2HPRP8p220Pre mRNA processing factor 8Pre mRNA-processing factor 8S. cerevisiaehomolog ofPre-mRNA-processing-splicing fa
Calculated MW
274 kDa
Observed MW
Refer to figures
Gene Accession
NP006436
Applications
Reactivity
Human, Mouse
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, ELISA 1:5000-1:10000
Concentration
0.5 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas