PTGS1 Polyclonal Antibody
Catalog Number
RD84434A
Immunohistochemistry of paraffin-embedded Human liver cancer using PTGS1 Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunofluorescence analysis of HeLa cells using PTGS1 Polyclonal Antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Variation
Quantity
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Overview
Product Name
PTGS1 Polyclonal Antibody
Catalog Number
RD84434A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, the encoded protein has been identified as a moonlighting protein. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants.
Immunogen Information
Immunogen
Recombinant fusion protein of human PTGS1 (NP_001258094.1).
Gene ID
5742
Swissprot
P23219
Synonyms
PTGS1COX1COX3PCOX1PES-1PGG/HSPGHS-1PGHS1PHS1PTGHS
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,IF
Conjugation
Unconjugated
Dilution
IHC 1:100-1:200 IF 1:50-1:200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas