RBM15 Polyclonal Antibody
Catalog Number
RD218870A
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using RBM15 Polyclonal Antibody at dilution of 1:70(×200)
Variation
Quantity
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Overview
Product Name
RBM15 Polyclonal Antibody
Catalog Number
RD218870A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
RNA-binding motif protein 15 (RBM15) belongs to the SPEN protein family,which have repressor function in several signaling pathway,and may bind to RNA through interaction with spliceosome components. It was first described as a 5′ translocation partner of the MAL gene in t(1,22)(p13;q13) infant acute megakaryocytic leukemia,and it functions in murine hematopoiesis through modulating Notch-induced transcriptional activation,which play crucial roles in leukemogenesis. Decreasing RBM15 levels with RNA interference could inhibit the growth and proliferation,block the cell cycle,and induce apoptosis in CML cells.
Immunogen Information
Immunogen
Fusion protein of human RBM15
Swissprot
Q96T37
Synonyms
One twenty two proteinOne-twenty two protein 1OTTOTT1Putative RNA-binding protein 15RBM15RBM15RNA binding motif protein 15RNA-binding motif protein 15
Gene Accession
BC006397
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:300, ELISA 1:5000-1:10000
Concentration
1.2 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas