REST Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue  using REST Polyclonal Antibody at dilution of 1:50(×200)
Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using REST Polyclonal Antibody at dilution of 1:50(×200)
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Overview

Circle
Product Name
REST Polyclonal Antibody
Catalog Number
RD217813A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit

Background

Circle
This gene encodes a transcriptional repressor that represses neuronal genes in non-neuronal tissues. It is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells and it is thought that this repressor may act as a master negative regular of neurogenesis. Alternatively spliced transcript variants have been described.

Immunogen Information

Circle
Immunogen
Synthetic peptide of human REST
Swissprot
Q13127
Synonyms
Neural Restrictive Silencer FactorNeural-restrictive silencer factorNeuron Restrictive Silencer FactorNRSFRE1 silencing transcription factorRE1-silencing transcription factorRepressor binding to the X2 boxrestREST proteinRESTX2 box repressorXBR
Gene Accession
NP005603

Applications

Circle
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:30-1:150, ELISA 1:5000-1:10000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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