RNASE1 Polyclonal Antibody
Catalog Number
RD253050A
Western blot analysis of Mouse pancreas tissue and Rat pancreas tissue lysates using RNASE1 Polyclonal Antibody at dilution of 1:550
Variation
Quantity
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Overview
Product Name
RNASE1 Polyclonal Antibody
Catalog Number
RD253050A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a member of the pancreatic-type of secretory ribonucleases, a subset of the ribonuclease A superfamily. The encoded endonuclease cleaves internal phosphodiester RNA bonds on the 3'-side of pyrimidine bases. It prefers poly(C) as a substrate and hydrolyzes 2',3'-cyclic nucleotides, with a pH optimum near 8.0. The encoded protein is monomeric and more commonly acts to degrade ds-RNA over ss-RNA. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.
Immunogen Information
Immunogen
Fusion protein of human RNASE1
Swissprot
P07998
Synonyms
HP-RNasePancreatic ribonucleaseRib 1RIB-1Rib1Ribonuclease 1Ribonuclease ARibonuclease a family 1Ribonuclease pancreaticRibonuclease RNase A family 1Ribonuclease RNase A family 1 pancreaticRNAS1_HUMANRNase 1RNase ARNase UpI-1Rnase1RNAseA
Calculated MW
18 kDa
Observed MW
Refer to figures
Gene Accession
BC005324
Applications
Reactivity
Human, Mouse, Rat
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, ELISA 1:5000-1:10000
Concentration
0.72 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas