RUNX2 Polyclonal Antibody
Catalog Number
RD230103A
Western Blot analysis of K562 cells with RUNX2 Polyclonal Antibody.
Immunofluorescence analysis of Human stomach tissue using RUNX2 Polyclonal Antibody at dilution of 1:200.
Variation
Quantity
For more information on our kits, please contact us at info@reddotbiotech.com
Overview
Product Name
RUNX2 Polyclonal Antibody
Catalog Number
RD230103A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis. Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters (By similarity). Inhibits MYST4-dependent transcriptional activation.
Immunogen Information
Immunogen
Synthesized peptide derived from the Internal region of human RUNX2.
Swissprot
Q13950
Synonyms
Acute myeloid leukemia 3 proteinAlpha subunit 1AML3CBF alpha 1CBF-alpha-1CBFA1CCDCCD1Cleidocranial dysplasia 1Core binding factorCore binding factor runt domain alpha subunit 1Core binding factor subunit alpha 1Core-binding factor subunit alph
Calculated MW
57 kDa
Observed MW
56 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IF,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IF 1:50-1:200, ELISA 1:20000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.