RUNX3 Polyclonal Antibody
Catalog Number
RD84407A
Western blot analysis of extracts of U-251MG cells using RUNX3 Polyclonal Antibody at dilution of 1:1000.
Immunofluorescence analysis of MCF-7 cells using RUNX3 Polyclonal Antibody
Variation
Quantity
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Overview
Product Name
RUNX3 Polyclonal Antibody
Catalog Number
RD84407A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants.
Immunogen Information
Immunogen
Recombinant fusion protein of human RUNX3 (NP_001026850.1).
Gene ID
864
Swissprot
Q13761
Synonyms
RUNX3AML2CBFA3PEBP2aC
Calculated MW
44 kDa/45 kDa
Observed MW
44 kDa
Applications
Reactivity
Human
Tested Applications
WB,IF
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000 IF 1:50-1:100
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas