TMED10 Polyclonal Antibody
Catalog Number
RD84070A
Immunohistochemistry of paraffin-embedded Rat kidney using TMED10 Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Mouse brain using TMED10 Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Human liver damage using TMED10 Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunofluorescence analysis of NIH-3T3 cells using TMED10 Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Variation
Quantity
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Overview
Product Name
TMED10 Polyclonal Antibody
Catalog Number
RD84070A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.
Immunogen Information
Immunogen
Recombinant fusion protein of human TMED10 (NP_006818.3).
Gene ID
10972
Swissprot
P49755
Synonyms
TMED10P24(DELTA)S31I125S31III125TMP21Tmp-21-Ip23p24d1
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,IF
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200 IF 1:50-1:200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas