TMED10 Polyclonal Antibody
Catalog Number
RD253096A
Western blot analysis of Raji Hela cell Mouse liver tissue Rat lung tissue Mouse Pancreas tissue NIH/3T3 cell lysates using TMED10 Polyclonal Antibody at dilution of 1:800
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TMED10 Polyclonal Antibody at dilution of 1:50(×200)
Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using TMED10 Polyclonal Antibody at dilution of 1:50(×200)
Variation
Quantity
For more information on our kits, please contact us at info@reddotbiotech.com
Overview
Product Name
TMED10 Polyclonal Antibody
Catalog Number
RD253096A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.
Immunogen Information
Immunogen
Fusion protein of human TMED10
Swissprot
P49755
Synonyms
1110014C03Rik21 kDa transmembrane trafficking protein21 kDa transmembrane-trafficking proteinMGC102351p23p24 family protein delta 1p24 family protein delta-1p24(DELTA)p24deltap24delta1S31I125S31III125TMED 10Tmed10TMEDATmp 21 ITmp 21Tmp
Calculated MW
25 kDa
Observed MW
Refer to figures
Gene Accession
BC001496
Applications
Reactivity
Human, Mouse, Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-1:200, ELISA 1:5000-1:10000
Concentration
0.9 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas