TNNI3 Polyclonal Antibody
Catalog Number
RD70475A
Western Blot analysis of various samples using TNNI3 Polyclonal Antibody at dilution of 1:600.
Variation
Quantity
For more information on our kits, please contact us at info@reddotbiotech.com
Overview
Product Name
TNNI3 Polyclonal Antibody
Catalog Number
RD70475A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).
Immunogen Information
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse Cardiac Troponin I
Swissprot
P19429,P48787,P23693
Synonyms
cardiac muscleCardiac troponin Icardiomyopathydilated 2A (autosomal recessive)Cardiomyopathyfamilial hypertrophic7includedCMD1FFCMD2ACMH7cTnIFamilial hypertrophic cardiomyopathy 7MGC116817RCM1Tn1TniTNN I3TNNC 1TNNC1TNNI3TNNI3Troponin
Calculated MW
24 kDa
Observed MW
28 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
140 μg/mL
Storage Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.