TP63 Polyclonal Antibody
Catalog Number
RD218722A
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using TP63 Polyclonal Antibody at dilution of 1:65(×200)
Variation
Quantity
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Overview
Product Name
TP63 Polyclonal Antibody
Catalog Number
RD218722A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
TP63,also named KET,P63,P73H,P73L and TP73L,belongs to the p53 family. It is a homologue of the tumor suppressor p53 and p73 genes. It is involved in malignancy acquisition and maintenance of cells. Unlike p53,the p63 gene encodes multiple isotypes with remarkably divergent abilities to transactivate p53 reporter genes and induce apoptosis. TP63 acts as a sequence specific DNA binding transcriptional activator or repressor. TP63 has 12 isoforms with MW 40kd(P40),50kd(P60),63kd(P63) and 73kd(P73L). It is Nuclear stain.
Immunogen Information
Immunogen
Fusion protein of human TP63
Swissprot
Q9H3D4
Synonyms
AISAmplified in squamous cell carcinomaB(p51A)B(p51B)Chronic ulcerative stomatitis proteinCUSPDN p63 alpha 1DNp63EEC3id:ibd3516Keratinocyte transcription factorKeratinocyte transcription factor KETKETLMSMGC115972MGC192897NBPOFC8OTTHUMP00
Gene Accession
NP001316074
Applications
Reactivity
Human, Mouse, Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200, ELISA 1:5000-1:10000
Concentration
1.14 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas