ZAP70 Polyclonal Antibody
Catalog Number
RD253219A
Western blot analysis of Jurkat cells using ZAP70 Polyclonal Antibody at dilution of 1:1000
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using ZAP70 Polyclonal Antibody at dilution of 1:50(×200)
Variation
Quantity
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Overview
Product Name
ZAP70 Polyclonal Antibody
Catalog Number
RD253219A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
Zeta-associated protein (ZAP)-70,a member of the Syk family of tyrosine kinases,plays an important role in T-cell receptor signaling,natural killer (NK) cell activation and early B-cell development. ZAP-70 is expressed in a subset of cases of chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) with unmutated immunoglobulin heavy-chain variable region (IgVH) genes and is associated with poor clinical outcome.
Immunogen Information
Immunogen
Synthetic peptide of human ZAP70
Swissprot
P43403
Synonyms
70 kDa zeta associated protein70 kDa zeta-associated proteinEC 2.7.10.2FLJ17670FLJ17679Selective T cell defectSRKSTDSyk related tyrosine kinaseSyk-related tyrosine kinaseTruncated ZAP kinaseTyrosine protein kinase ZAP70Tyrosine-protein kinase
Calculated MW
70 kDa
Observed MW
Refer to figures
Gene Accession
NP001070
Applications
Reactivity
Human, Mouse
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:2000-1:5000
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas