ZFAND5 Polyclonal Antibody
Catalog Number
RD218321A
Western blot analysis of Mouse fat tissue lysate using ZFAND5 Polyclonal Antibody at dilution of 1:500
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using ZFAND5 Polyclonal Antibody at dilution of 1:35(×200)
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using ZFAND5 Polyclonal Antibody at dilution of 1:35(×200)
Variation
Quantity
For more information on our kits, please contact us at info@reddotbiotech.com
Overview
Product Name
ZFAND5 Polyclonal Antibody
Catalog Number
RD218321A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
Involved in protein degradation via the ubiquitin-proteasome system. May act by anchoring ubiquitinated proteins to the proteasome. Plays a role in ubiquitin-mediated protein degradation during muscle atrophy. Plays a role in the regulation of NF-kappa-B activation and apoptosis. Inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. Inhibits also tumor necrosis factor (TNF), IL-1 and TLR4-induced NF-kappa-B activation in a dose-dependent manner. Overexpression sensitizes cells to TNF-induced apoptosis. Is a potent inhibitory factor for osteoclast differentiation.
Immunogen Information
Immunogen
Full length fusion protein
Swissprot
O76080
Synonyms
AN1-type zinc finger protein 5ZA20D2ZFAN5Zfand5ZFAND5Azinc finger A20 domain containing 2Zinc finger A20 domain containing protein 2Zinc finger A20 domain-containing protein 2zinc finger AN1 type domain 5Zinc finger protein 216ZNF216
Calculated MW
23 kDa
Observed MW
Refer to figures
Gene Accession
BC011018
Applications
Reactivity
Human, Mouse, Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000
Concentration
1.4 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.